Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NA |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | EC tissues,cell lines (HEC-1A, HEC-1B, Ishikawa, RL-95-2 and JEC) |
| Expression Pattern | up-regulated |
| Function Description | NEAT1 was highly expressed in EC tissues and cells. NEAT1 promotes EC cells proliferation and invasion by regulating the miR-144-3p/EZH2 axis. |
| Pubmed ID | 31747378 |
| Year | 2019 |
| Title | LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |