Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cholangiocarcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RNAi, RIP, ChIP |
| Sample | CCA tissues, cell lines (QBC939, RBE, Hu CCT1, TFK-1, HIBEpic) |
| Expression Pattern | up-regulated |
| Function Description | NEAT1 expression was higher in CCA tumors than matched adjacent non-tumor tissue.therapeutic procedures that have been accomplished for CCA in recent years, overall survival rates of CCA patients is quite poor due to recurrence and metastasis |
| Pubmed ID | 28810932 |
| Year | 2039 |
| Title | LncRNA NEAT1 Promotes Growth and Metastasis of Cholangiocarcinoma Cells. |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for cholangiocarcinoma | OMIM COSMIC |