Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR etc. |
| Sample | ovarian cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | NEAT1 is upregulated in ovarian cancer tissues compared with the corresponding adjacent non-neoplastic tissues. The expression level of NEAT1 was positively correlated with FIGO stage, tumor grade and distant metastasis. |
| Pubmed ID | 27608895 |
| Year | 2016 |
| Title | Clinical significance of up-regulated lncRNA NEAT1 in prognosis of ovarian cancer. |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |