Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, RNAi etc. |
| Sample | cell line (A549) |
| Expression Pattern | differential expression |
| Function Description | Our result showed that, the level of NEAT1 was up-regulated when the knockdown of miR-449a; on the contrary, the expression of NEAT1 was down-regulated when miR-449a was the overexpression. |
| Pubmed ID | 25818739 |
| Year | 2014 |
| Title | MicroRNA-449a inhibits cell growth in lung cancer and regulates long noncoding RNA nuclear enriched abundant transcript 1. |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |