Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR etc. |
| Sample | lung cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | The relative level of NEAT1 in NSCLC tissues was significantly elevated as compared to that of the adjacent non-cancer lung tissues. NEAT1 expression was positively correlated with patient age, lymphatic metastasis, vascular invasion and clinical TNM stage. lncRNA NEAT1 may act as a oncogene, which plays an important role in the tumorigenesis and deterioration of human NSCLC. |
| Pubmed ID | 25854373 |
| Year | 2015 |
| Title | Upregulation and Clinicopathological Significance of Long Non-coding NEAT1 RNA in NSCLC Tissues. |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |