Basic Information
| LncRNA/CircRNA Name | NKILA |
| Synonyms | NA |
| Region | GRCh38_20:57710183-57712780 |
| Ensemble | ENSG00000278709 |
| Refseq | NR_131157 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, Western blot |
| Sample | HCC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | NKILA prevents Slug/epithelial to mesenchymal transition (EMT) pathway via suppressing phosphorylation of I?B?, p65 nuclear translocation and NF-?B activation. |
| Pubmed ID | 32015685 |
| Year | 2020 |
| Title | NKILA, a prognostic indicator, inhibits tumor metastasis by suppressing NF-?B/Slug mediated epithelial-mesenchymal transition in hepatocellular carcinoma |
External Links
| Links for NKILA | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |