Basic Information
| LncRNA/CircRNA Name | NKILA |
| Synonyms | NA |
| Region | GRCh38_20:57710183-57712780 |
| Ensemble | ENSG00000278709 |
| Refseq | NR_131157 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | RT-qPCR, Western blotting |
| Sample | bronchial epithelial cell line (16HBE) and NSCLC adenocarcinoma cell lines (A549, NCI-H1975) |
| Expression Pattern | down-regulated |
| Function Description | The expression of NKILA was significantly down regulated in lung cancer tissues when compared to matched normal tissue.low expression of lncRNA NKILA plays a role in the deterioration of NSCLC cells and this effect depends on IL-11/STAT3 signaling. |
| Pubmed ID | 31934087 |
| Year | 2019 |
| Title | Long Non-Coding RNA NKILA Inhibits Proliferation and Migration of Lung Cancer via IL-11/STAT3 Signaling |
External Links
| Links for NKILA | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |