Basic Information
| LncRNA/CircRNA Name | NKILA |
| Synonyms | AK056098 |
| Region | GRCh38_20:57710183-57712780 |
| Ensemble | ENSG00000278709 |
| Refseq | NR_131157 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, RIP |
| Sample | non-small cell lung cancer tissues, cell lines (H226, H292, H460, A549, ANP973 and H1299) |
| Expression Pattern | down-regulated |
| Function Description | The expression of NKILA was down-regulated in NSCLC cancer tissues compared with matched adjacent noncancerous tissues, and lower NKILA expression in tumor tissues were significantly correlated with lymph node metastasis and advanced TNM stage. |
| Pubmed ID | 28412955 |
| Year | 2017 |
| Title | Long non-coding RNA NKILA inhibits migration and invasion of non-small cell lung cancer via NF-kB/Snail pathway |
External Links
| Links for NKILA | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |