Basic Information
| LncRNA/CircRNA Name | NNT-AS1 |
| Synonyms | NA |
| Region | GRCh38_5:43571594-43603230 |
| Ensemble | ENSG00000248092 |
| Refseq | NR_073113 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cholangiocarcinoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | CCA tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | NNT-AS1 promoted proliferation, EMT and PI3K/AKT and ERK1/2 pathways in CCLP1 and TFK1 cells through down-regulating miR-203. |
| Pubmed ID | 32019904 |
| Year | 2020 |
| Title | Long non-coding RNA NNT-AS1 promotes cholangiocarcinoma cells proliferation and epithelial-to-mesenchymal transition through down-regulating miR-203 |
External Links
| Links for NNT-AS1 | GenBank HGNC NONCODE |
| Links for cholangiocarcinoma | OMIM COSMIC |