Basic Information
| LncRNA/CircRNA Name | NORAD |
| Synonyms | NA |
| Region | GRCh38_20:36045622-36050960 |
| Ensemble | ENSG00000260032 |
| Refseq | NR_027451 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Western blot |
| Sample | PCA cell lines LNCaP, 22Rv1, PC-3, and DU145 and normal prostate epithelial cells (RWPE-1) |
| Expression Pattern | up-regulated |
| Function Description | Cell proliferation and migration rates were significantly lower in the siNORAD group than in the wild-type group, while the apoptosis level was significantly higher in the siNORAD group compared with the wild-type group. |
| Pubmed ID | 31342822 |
| Year | 2019 |
| Title | Long non-coding RNA NORAD induces cell proliferation and migration in prostate cancer |
External Links
| Links for NORAD | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |