Basic Information
| LncRNA/CircRNA Name | NR_029373 |
| Synonyms | LEF1-AS1, LEF1NAT |
| Region | GRCh38_4:108167525-108256836 |
| Ensemble | ENSG00000232021 |
| Refseq | NR_029373 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR etc. |
| Sample | CRC tissues |
| Expression Pattern | down-regulated |
| Function Description | The expression of all 18 candidate lncRNAs was evaluated by RT-qPCR, using 80 pairs of CRC and control tissue samples. Among these, eight lncRNAs (MALAT-1, NR_029373, NR_046321, NR_034119, GAS5, BANCR, NR_026817 and PCAT-1) were found significantly dysregulated in CRC tumor tissues compared with controls. |
| Pubmed ID | 27591862 |
| Year | 2016 |
| Title | Identification of long noncoding RNAs as potential novel diagnosis and prognosis biomarkers in colorectal cancer. |
External Links
| Links for NR_029373 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |