Basic Information
| LncRNA/CircRNA Name | NR2F2-AS1 |
| Synonyms | NA |
| Region | GRCh38_15:96110040-96327361 |
| Ensemble | ENSG00000247809 |
| Refseq | XR_109225 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | RT-qPCR |
| Sample | ccRCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | NR2F2-AS1 and Rac1 overexpression resulted in the increased ccRCC cell stemness, whereas NR2F2-AS1 and Rac1 siRNA silencing played an opposite role. Rac1 overexpression inhibited the role of NR2F2-AS1 siRNA silencing. |
| Pubmed ID | 32109138 |
| Year | 2020 |
| Title | LncRNA NR2F2-AS1 Upregulates Rac1 to Increase Cancer Stemness in Clear Cell Renal Cell Carcinoma |
External Links
| Links for NR2F2-AS1 | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |