Basic Information
| LncRNA/CircRNA Name | OIP5-AS1 |
| Synonyms | NA |
| Region | GRCh38_15:41283990-41309737 |
| Ensemble | ENSG00000247556 |
| Refseq | NR_026757 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR, Western blot |
| Sample | GC tissues,cell lines (NCI-N87, MKN-45, BGC-823 and SGC-7901) |
| Expression Pattern | up-regulated |
| Function Description | OIP5-AS1 functions as an oncogenic competing endogenous RNA by binding to and sequestering miR-422a to elevate the expression of anoctamin-1.high OIP5 AS1 expression was positively associated with tumor size and tumor node metastasis (TNM) stage. |
| Pubmed ID | 32147682 |
| Year | 2020 |
| Title | LncRNA OIP5-AS1 facilitates gastric cancer cell growth by targeting the miR-422a/ANO1 axis |
External Links
| Links for OIP5-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |