Basic Information
| LncRNA/CircRNA Name | OIP5-AS1 |
| Synonyms | NA |
| Region | GRCh38_15:41283990-41309737 |
| Ensemble | ENSG00000247556 |
| Refseq | NR_026757 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc. |
| Sample | HCC and adjacent normal tissue, cell lines(HL-7702,HepG2, HCCLM3, Huh7, Hep3B, and HCCLM6) |
| Expression Pattern | up-regulated |
| Function Description | In the first place, qRT-PCR found that OIP5-AS1 and VEGFA expressions were significantly increased while miR-3163 was obviously reduced in HCC cells and tissues.OIP5-AS1 accelerates HCC progression via competitively interacting with miR-3163. |
| Pubmed ID | 32329664 |
| Year | 2020 |
| Title | LncRNA OIP5-AS1 promotes cell proliferation and migration and induces angiogenesis via regulating miR-3163/VEGFA in hepatocellular carcinoma. |
External Links
| Links for OIP5-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |