Basic Information
| LncRNA/CircRNA Name | OLBC15 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | triple negative breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, RIP etc |
| Sample | breast cancer cell lines(MCF-10A,MDA-MB-231, BT549, HCC1806, Hs578t, MDA-MB-468),breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | OLBC15 is highly expressed especially in triple-negative breast cancer. OLBC15 promoted viability and migration in breast cancer cells. Moreover, OLBC15 could accelerate metastasis and xenograft tumor growth. |
| Pubmed ID | 32329931 |
| Year | 2020 |
| Title | A long non-coding RNA OLBC15 promotes triple-negative breast cancer progression via enhancing ZNF326 degradation. |
External Links
| Links for OLBC15 | GenBank HGNC NONCODE |
| Links for triple negative breast cancer | OMIM COSMIC |