Basic Information
| LncRNA/CircRNA Name | P14AS |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | RNA sequencing, RIP |
| Sample | colon cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | A novel lncRNA, P14AS, transcribed from the antisense strand of the CDKN2A/P14 gene, promotes colon cancer development by cis upregulating the expression of oncogenic ANRIL. |
| Pubmed ID | 32106863 |
| Year | 2020 |
| Title | Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells |
External Links
| Links for P14AS | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |