Basic Information
LncRNA/CircRNA Name | PART1 |
Synonyms | NA |
Region | GRCh38_5:60487713-60547657 |
Ensemble | ENSG00000152931 |
Refseq | NR_024617 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | glioma |
ICD-0-3 | NA |
Methods | RT-qPCR, Western blot |
Sample | glioma tissues,cell lines |
Expression Pattern | down-regulated |
Function Description | PART1 suppressed cell proliferation and triggered cell apoptosis in glioma cell lines.PART1 inactivated PI3K/AKT cascade in glioma cell lines. |
Pubmed ID | 32099409 |
Year | 2020 |
Title | Long Non-Coding RNA PART1 Exerts Tumor Suppressive Functions in Glioma via Sponging miR-190a-3p and Inactivation of PTEN/AKT Pathway |
External Links
Links for PART1 | GenBank HGNC NONCODE |
Links for glioma | OMIM COSMIC |