Basic Information
| LncRNA/CircRNA Name | PCA3 |
| Synonyms | PCA3, DD3, NCRNA00019, PCAT3 |
| Region | GRCh38_9:76691980-76863307 |
| Ensemble | ENSG00000225937 |
| Refseq | NR_015342 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Northern blot etc. |
| Sample | BPH, prostatic tumor tissues |
| Expression Pattern | up-regulated |
| Function Description | Our data indicate that DD3 is one of the most prostate cancer-specific genes yet described, and this makes DD3 a promising marker for the early diagnosis of prostate cancer and provides a powerful tool for the development of new treatment strategies for prostate cancer patients. |
| Pubmed ID | 10606244 |
| Year | 1999 |
| Title | DD3: a new prostate-specific gene, highly overexpressed in prostate cancer. |
External Links
| Links for PCA3 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |