Basic Information
| LncRNA/CircRNA Name | PCAT1 |
| Synonyms | LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1 |
| Region | GRCh38_8:126556323-127419050 |
| Ensemble | ENSG00000253438 |
| Refseq | NR_045262 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, RNA-seq, RIP |
| Sample | Prostate tissue,cell line(LNCaP,C4-2) |
| Expression Pattern | up-regulated |
| Function Description | We conducted differential expression analysis of lncRNAs between LNCaP-AI cells and their parental LNCaP cells, and found that PCAT1 was significantly upregulated in LNCaP-AI cells |
| Pubmed ID | 30773595 |
| Year | 2019 |
| Title | LncRNA PCAT1 activates AKT and NF-?B signaling in castration-resistant prostate cancer by regulating the PHLPP/FKBP51/IKK? complex. |
External Links
| Links for PCAT1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |