Basic Information
| LncRNA/CircRNA Name | PCAT1 |
| Synonyms | LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1 |
| Region | GRCh38_8:126556323-127419050 |
| Ensemble | ENSG00000253438 |
| Refseq | NR_045262 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR etc. |
| Sample | bladder cancer cell lines (5637, T24), bladder cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | This study indicates that genetic variants in lncRNA PCAT1 were associated with bladder cancer susceptibility and the SNP rs710886 may act as a potential biomarker for bladder cancer risk.Single nucleotide polymorphisms (SNPs) are the most common genetic variants.f genes. Accumulated evidence hasshownthat plenty of functional SNPs are converged upon lncRNAs and responsible for bladder cancer carcinogenesis [17]. |
| Pubmed ID | 28627442 |
| Year | 2017 |
| Title | The association of rs710886 in lncRNA PCAT1 with bladder cancer risk in a Chinese population. |
External Links
| Links for PCAT1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |