Basic Information
| LncRNA/CircRNA Name | PCAT6 |
| Synonyms | NA |
| Region | GRCh38_1:202810954-202812156 |
| Ensemble | ENSG00000228288 |
| Refseq | NR_046325 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RT-qPCR, Western blot |
| Sample | GC tissues |
| Expression Pattern | up-regulated |
| Function Description | PCAT6 was a?target of miR-15a. Silencing of lncRNA PCAT6 restrained proliferation and EMT of GC cells by targeting miR-15a via RB/E2F and Wnt/?-catenin pathways. |
| Pubmed ID | 32039820 |
| Year | 2020 |
| Title | Silencing of long non-coding RNA PCAT6 restrains gastric cancer cell proliferation and?epithelial-mesenchymal transition by targeting microRNA-15a |
External Links
| Links for PCAT6 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |