Basic Information
| LncRNA/CircRNA Name | PCAT6 |
| Synonyms | NA |
| Region | GRCh38_1:202810954-202812156 |
| Ensemble | ENSG00000228288 |
| Refseq | NR_046325 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | LIHC tissues,cell lines (HepG2 and SMMC-7721) |
| Expression Pattern | up-regulated |
| Function Description | We found that PCAT6 was significantly up-regulated in LIHC tissues and predicted a poorer survival in TCGA data. Knockdown of PCAT6 in LIHC cell lines could inhibit cell growth and migration. |
| Pubmed ID | 30968586 |
| Year | 2019 |
| Title | Gene amplification derived a cancer-testis long noncoding RNA PCAT6 regulates cell proliferation and migration in hepatocellular carcinoma. |
External Links
| Links for PCAT6 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |