Basic Information
| LncRNA/CircRNA Name | PCAT6 |
| Synonyms | PCAT6, KDM5B-AS1, KDM5BAS1, PCAN-R1, ncRNA-a2, onco-lncRNA-96 |
| Region | GRCh38_1:202810954-202812156 |
| Ensemble | ENSG00000228288 |
| Refseq | NR_046325 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR etc. |
| Sample | LUAD tissues |
| Expression Pattern | up-regulated |
| Function Description | Circulating PCAT6 play a pivotal role in carcinogenesis and progression of NSCLC. PCAT6 regulates p53 and c-myc expressions in an indirect manner. |
| Pubmed ID | 29238201 |
| Year | 2017 |
| Title | Diagnostic signifcance of circulating long noncoding RNA PcaT6 in patients with non-small cell lung cancer |
External Links
| Links for PCAT6 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |