Basic Information
| LncRNA/CircRNA Name | PCNA-AS1 |
| Synonyms | PCNA-AS1, PCNA-AS, PCNAAS |
| Region | GRCh38_20:5119586-5119969 |
| Ensemble | NA |
| Refseq | NR_028370 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (Huh7, SMMC7721) |
| Expression Pattern | up-regulated |
| Function Description | PCNA-AS1 was up-regulated in HCC and its expression status was associated with multiple tumor nodules. The effects of PCNA-AS1 rely on regulation of PCNA via forming RNA hybridization to increase PCNA mRNA stability. |
| Pubmed ID | 24704293 |
| Year | 2014 |
| Title | Antisense long non-coding RNA PCNA-AS1 promotes tumor growth by regulating proliferating cell nuclear antigen in hepatocellular carcinoma. |
External Links
| Links for PCNA-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |