Basic Information
| LncRNA/CircRNA Name | PINCR |
| Synonyms | NA |
| Region | GRCh38_X:43176994-43226598 |
| Ensemble | ENSG00000224294 |
| Refseq | NR_110387 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot, Luciferase reporter assays |
| Sample | cell lines (HCT116, SW48, RKO, HEK293T) |
| Expression Pattern | differential expression |
| Function Description | Targeted deletion of PINCR in CRC cells significantly impaired G1 arrest and induced hypersensitivity to chemotherapeutic drugs. |
| Pubmed ID | 28580901 |
| Year | 2017 |
| Title | Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 |
External Links
| Links for PINCR | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |