Basic Information
| LncRNA/CircRNA Name | POLR2E |
| Synonyms | NA |
| Region | GRCh38_19:1086579-1095380 |
| Ensemble | ENSG00000099817 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | papillary thyroid carcinoma tissues |
| Expression Pattern | differential expression |
| Function Description | The meta-analysis further revealed that POLR2E rs3787016T allele was associated with an increased cancer risk in Chinese population. Collectively, the POLR2E rs3787016 may be used as a genetic biomarker to predict cancer risk in Chinese population. |
| Pubmed ID | 29724531 |
| Year | 2018 |
| Title | Long non-coding RNA POLR2E rs3787016 is associated with the risk of papillary thyroid carcinoma in Chinese population. |
External Links
| Links for POLR2E | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |