Basic Information
| LncRNA/CircRNA Name | LINC-POU3F3 |
| Synonyms | POU3F3, BRN1, OTF8, brain-1, oct-8 |
| Region | GRCh38_2:104855511-104858574 |
| Ensemble | ENSG00000198914 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR |
| Sample | TNBC tissues |
| Expression Pattern | up-regulated |
| Function Description | In addition, plasma levels of lncRNA POU3F3 were higher in TNBC patients than in healthy controls and were significantly and inversely correlated with levels of cleaved caspase 9 only in TNBC patients. |
| Pubmed ID | 30843771 |
| Year | 2019 |
| Title | LncRNA POU3F3 promotes proliferation and inhibits apoptosis of cancer cells in triple-negative breast cancer by inactivating caspase 9. |
External Links
| Links for LINC-POU3F3 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |