Basic Information
LncRNA/CircRNA Name | LINC-POU3F3 |
Synonyms | POU3F3, BRN1, OTF8, brain-1, oct-8 |
Region | GRCh38_2:104855511-104858574 |
Ensemble | ENSG00000198914 |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR |
Sample | TNBC tissues |
Expression Pattern | up-regulated |
Function Description | In addition, plasma levels of lncRNA POU3F3 were higher in TNBC patients than in healthy controls and were significantly and inversely correlated with levels of cleaved caspase 9 only in TNBC patients. |
Pubmed ID | 30843771 |
Year | 2019 |
Title | LncRNA POU3F3 promotes proliferation and inhibits apoptosis of cancer cells in triple-negative breast cancer by inactivating caspase 9. |
External Links
Links for LINC-POU3F3 | GenBank HGNC NONCODE |
Links for breast cancer | OMIM COSMIC |