Basic Information
| LncRNA/CircRNA Name | POU6F2-AS2 |
| Synonyms | NA |
| Region | GRCh38_7:38984243-39013551 |
| Ensemble | ENSG00000233854 |
| Refseq | NR_138047 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | RT-qPCR |
| Sample | colon cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | Up-regulated POU6F2-AS2 promoted cell proliferation and cell cycle of colon cancer cells. Overexpression of POU6F2-AS2 inhibited the expression of miR-377 and then up-regulated the expression of BRD4. |
| Pubmed ID | 32100443 |
| Year | 2020 |
| Title | Long non-coding RNA POU6F2-AS2 promotes cell proliferation and drug resistance in colon cancer by regulating miR-377/BRD4 |
External Links
| Links for POU6F2-AS2 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |