Basic Information
| LncRNA/CircRNA Name | PRKCQ-AS1 |
| Synonyms | NA |
| Region | GRCh38_10:6580419-6616452 |
| Ensemble | ENSG00000237943 |
| Refseq | NR_036502 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-qPCR |
| Sample | CRC tissues |
| Expression Pattern | up-regulated |
| Function Description | Upregulation of PRKCQ-AS1 was related to a significant decrease in survival of colorectal cancer (CRC) patients. Since a significantly concordant expression was observed for SATB1-AS1 and SATB1 in only cancerous, and for PRKCQ-AS1 and PRKCQ in both normal and cancerous colorectal tissues, it can be concluded that common mechanisms may regulate the expression of these sense and antisense genes. |
| Pubmed ID | 31708689 |
| Year | 2019 |
| Title | Expression profile analysis of?two antisense lncRNAs to?improve prognosis prediction of?colorectal adenocarcinoma |
External Links
| Links for PRKCQ-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |