Basic Information
| LncRNA/CircRNA Name | PRRT3-AS1 |
| Synonyms | NA |
| Region | GRCh38_3:9947404-9954787 |
| Ensemble | ENSG00000230082 |
| Refseq | NR_046734 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | autophagy,apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | RT-qPCR, Western blot, Microarray |
| Sample | PC cell lines |
| Expression Pattern | up-regulated |
| Function Description | PPAR? was predicted as a target gene of lncRNA PRRT3-AS1. Ectopic overexpression of PPAR? or lncRNA PRRT3-AS1 silencing led to inhibited cell viability, migration and invasion, and accelerated apoptosis. |
| Pubmed ID | 32086850 |
| Year | 2020 |
| Title | Long noncoding RNA PRRT3-AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagy |
External Links
| Links for PRRT3-AS1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |