Basic Information
| LncRNA/CircRNA Name | PSMB8-AS1 |
| Synonyms | NA |
| Region | GRCh38_6:32844086-32846495 |
| Ensemble | ENSG00000204261 |
| Refseq | NR_037173 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, Western blot |
| Sample | glioblastoma tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | overexpression of PSMB8-AS1 promoted the level of DDIT4 through inhibiting miR-22-3p. Rescue assays demonstrated that overexpression of DDIT4 counteracted the impact of proliferation, apoptosis and radioresistance silencing PSMB8-AS1 lay on glioblastoma cell. |
| Pubmed ID | 32151711 |
| Year | 2020 |
| Title | LncRNA PSMB8-AS1 acts as ceRNA of miR-22-3p to regulate DDIT4 expression in glioblastoma |
External Links
| Links for PSMB8-AS1 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |