Basic Information
| LncRNA/CircRNA Name | BCYRN1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000236824 |
| Refseq | NR_001568 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot etc |
| Sample | CRC tissues, cell line (SW620) |
| Expression Pattern | up-regulated |
| Function Description | LncRNA BCYRN1 expression was markedly up-regulated in CRC; high expression of lncRNA BCYRN1 promoted tumor metastasis in CRC patients and suggested a poor prognosis. In vitro study, down-regulation of lncRNA BCYRN1 expression by si-BCYRN1 could significantly inhibit invasion and migration of CRC cells. |
| Pubmed ID | 31773686 |
| Year | 2019 |
| Title | Clinical Significance of lncRNA BCYRN1 in Colorectal Cancer and Its Role in Cell Metastasis |
External Links
| Links for BCYRN1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |