Basic Information
| LncRNA/CircRNA Name | BCYRN1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000236824 |
| Refseq | NR_001568 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR, Western blot |
| Sample | colorectal cancer tissues, cell lines (GEO, SW480, LOVO, NCM460) |
| Expression Pattern | up-regulated |
| Function Description | The results showed that BCYRN1 expression was significantly upregulated in 96 CRC tumor tissues compared with para-carcinoma control tissues. In vitro BCYRN1 knockdown significantly inhibited the proliferation and apoptosis of CRC cells. |
| Pubmed ID | 30114690 |
| Year | 2018 |
| Title | Long Noncoding RNA BCYRN1 Promotes the Proliferation of Colorectal Cancer Cells via Up-Regulating NPR3 Expression. |
External Links
| Links for BCYRN1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |