Basic Information
| LncRNA/CircRNA Name | PTTG3P |
| Synonyms | PTTG3??cPTTG1 |
| Region | GRCh38_8:66767400-66768005 |
| Ensemble | ENSG00000213005 |
| Refseq | NR_002734 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot etc. |
| Sample | hepatocellular carcinoma tissues, cell lines (HepG2 and Hep3B) |
| Expression Pattern | up-regulated |
| Function Description | We found that PTTG3P was frequently up-regulated in HCC and its level was positively correlated to tumor size, TNM stage and poor survival of patients with HCC. |
| Pubmed ID | 29803224 |
| Year | 2018 |
| Title | The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma |
External Links
| Links for PTTG3P | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |