Basic Information
LncRNA/CircRNA Name | PVT1 |
Synonyms | NA |
Region | GRCh38_8:127794533-128101253 |
Ensemble | ENSG00000249859 |
Refseq | NR_003367 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | 2 | ||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | anaplastic thyroid cancer |
ICD-0-3 | C73 |
Methods | qPCR, other |
Sample | anaplastic thyroid cancer cell lines (TPC-1 and THJ-16T) |
Expression Pattern | up-regulated |
Function Description | Additionally, the cells were examined for lncRNA expression after 6 days of treatment by RT-qPCR revealing a significant upregulation in 3 lncRNAs(MALAT1, PVT1 and linc-ROR) studied. |
Pubmed ID | 29967342 |
Year | 2018 |
Title | Thyroid Cancer Stem-Like Cell Exosomes: Regulation of EMT via Transfer of lncRNAs |
External Links
Links for PVT1 | GenBank HGNC NONCODE |
Links for anaplastic thyroid cancer | OMIM COSMIC |