Basic Information
| LncRNA/CircRNA Name | PVT1 |
| Synonyms | NA |
| Region | GRCh38_8:127794533-128101253 |
| Ensemble | ENSG00000249859 |
| Refseq | NR_003367 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute lymphoblastic leukemia |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RNAi |
| Sample | ALL cell line |
| Expression Pattern | up-regulated |
| Function Description | The results demonstrate higher expression of PVT1 lncRNA in the ALL cell line than in normal cells. |
| Pubmed ID | 30930624 |
| Year | 2019 |
| Title | Long noncoding RNA PVT1: potential oncogene in the development of acute lymphoblastic leukemia. |
External Links
| Links for PVT1 | GenBank HGNC NONCODE |
| Links for acute lymphoblastic leukemia | OMIM COSMIC |