Basic Information
| LncRNA/CircRNA Name | PVT1 |
| Synonyms | NA |
| Region | GRCh38_8:127794533-128101253 |
| Ensemble | ENSG00000249859 |
| Refseq | NR_003367 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gallbladder cancer |
| ICD-0-3 | C23.9 |
| Methods | qPCR, RIP |
| Sample | GBC tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | PVT1 was upregulated in GBC tissues and cells and was positively associated with malignancies and worse overall survival. |
| Pubmed ID | 30825877 |
| Year | 2019 |
| Title | Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer. |
External Links
| Links for PVT1 | GenBank HGNC NONCODE |
| Links for gallbladder cancer | OMIM COSMIC |