Basic Information
LncRNA/CircRNA Name | PVT1 |
Synonyms | NA |
Region | GRCh38_8:127794533-128101253 |
Ensemble | ENSG00000249859 |
Refseq | NR_003367 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 |
Methods | qPCR |
Sample | HCC tissues,cell line |
Expression Pattern | up-regulated |
Function Description | Our study found PVT1 levels were markedly up-regulated in the corresponding HCC tissues. Importantly, we found that PVT1 could facilitate cell autophagy in HCC cells. |
Pubmed ID | 30794914 |
Year | 2019 |
Title | Long non-coding RNA PVT1 promotes autophagy as ceRNA to target ATG3 by sponging microRNA-365 in hepatocellular carcinoma. |
External Links
Links for PVT1 | GenBank HGNC NONCODE |
Links for hepatocellular carcinoma | OMIM COSMIC |