Basic Information
| LncRNA/CircRNA Name | RAET1K |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, RNA isolation |
| Sample | HCC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | LncRNA RAET1K silencing significantly suppressed HCC cell proliferation and invasion and also suppressed hypoxia-induced increases in lactate concentration and glucose uptake, while miR-100-5p inhibition reversed the effects of lncRNA RAET1K silencing on hypoxia induced glycolysis in HCC cells. |
| Pubmed ID | 32152275 |
| Year | 2020 |
| Title | HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p |
External Links
| Links for RAET1K | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |