Basic Information
| LncRNA/CircRNA Name | RC3H2 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qRT-PCR, Western blot |
| Sample | OSCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | RC3H2 overexpression significantly promoted OSCC cell growth, colony formation, migration, invasion, and xenograft tumor growth in vivo and increased the expression of EZH2 and H3K27Me3. |
| Pubmed ID | 32163895 |
| Year | 2020 |
| Title | Long Noncoding RNA RC3H2 Facilitates Cell Proliferation and Invasion by Targeting MicroRNA-101-3p/EZH2 Axis in OSCC |
External Links
| Links for RC3H2 | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |