Basic Information
| LncRNA/CircRNA Name | RGMB-AS1 |
| Synonyms | NA |
| Region | GRCh38_5:98769618-98773469 |
| Ensemble | ENSG00000246763 |
| Refseq | NR_033932 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RT-qPCR, Western blot |
| Sample | GC cell lines (AGS, BGC-823, SGC7901, MGC-803) |
| Expression Pattern | up-regulated |
| Function Description | RGMB-AS1 was upregulated in GC cells and knockdown of RGMB-AS1 suppressed cell proliferation, migration, invasion, EMT process and promoted cell apoptosis. |
| Pubmed ID | 32064882 |
| Year | 2019 |
| Title | RGMB-AS1/miR-22-3p/NFIB axis contributes to the progression of gastric cancer |
External Links
| Links for RGMB-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |