Basic Information
| LncRNA/CircRNA Name | RGMB-AS1 |
| Synonyms | NA |
| Region | GRCh38_5:98769618-98773469 |
| Ensemble | ENSG00000246763 |
| Refseq | NR_033932 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | Microarray, qPCR, Western blot etc. |
| Sample | NSCLC tissues, cell lines (A549 and SPC-A-1) |
| Expression Pattern | up-regulated |
| Function Description | LncRNA RGMB-AS1 expression was significantly higher in NSCLC tissues than in adjacent normal tissues, lncRNA RGMB-AS1 and RGMB expression levels in NSCLC tissues were associated with the occurrence of differentiation status, lymph node metastases and TNM stage. Studies also indicated that lncRNA RGMB-AS1and RGMB were inversely correlated. |
| Pubmed ID | 26055877 |
| Year | 2015 |
| Title | Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer. |
External Links
| Links for RGMB-AS1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |