Basic Information
| LncRNA/CircRNA Name | RHPN1-AS1 |
| Synonyms | NA |
| Region | GRCh38_8:143366631-143368548 |
| Ensemble | ENSG00000254389 |
| Refseq | NR_026785 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR, Western blot |
| Sample | GC tissues,cell lines (BGC-823, AGS, MGC-803 and SGC-7901) |
| Expression Pattern | up-regulated |
| Function Description | The expression of RHPN1-AS1 was significantly upregulated in GC samples and cells.RHPN1-AS1/miR-1299/ETS1 positive feedback loop aggravated the malignant behaviors of GC, revealing RHPN1-AS1 as a latent effective target for the treatment of GC patients. |
| Pubmed ID | 31982726 |
| Year | 2020 |
| Title | The positive feedback loop of RHPN1-AS1/miR-1299/ETS1 accelerates the deterioration of gastric cancer |
External Links
| Links for RHPN1-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |