Basic Information
| LncRNA/CircRNA Name | RHPN1-AS1 |
| Synonyms | RHPN1-AS1, C8orf51 |
| Region | GRCh38_8:143366631-143368548 |
| Ensemble | ENSG00000254389 |
| Refseq | NR_026785 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | uveal melanoma |
| ICD-0-3 | C69.9 |
| Methods | qPCR, RNAi, Cell migration and invasion assay etc. |
| Sample | cell lines (OM431, OCM1 and RPE) |
| Expression Pattern | up-regulated |
| Function Description | RHPN1-AS1 was significantly upregulated in a number of UM cell lines compared with the normal human retinal pigment epithelium (RPE) cell line. RHPN1-AS1 knockdown significantly inhibited UM cell proliferation and migration in vitro and in vivo. |
| Pubmed ID | 28124977 |
| Year | 2017 |
| Title | The Long Non-Coding RNA RHPN1-AS1 Promotes Uveal Melanoma Progression. |
External Links
| Links for RHPN1-AS1 | GenBank HGNC NONCODE |
| Links for uveal melanoma | OMIM COSMIC |