Basic Information
| LncRNA/CircRNA Name | RNA-14327.1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | RIP, Western blotting, qRT-PCR |
| Sample | endometrial carcinoma biopsy specimens,endometrial carcinoma cell line HEC-1A |
| Expression Pattern | up-regulated |
| Function Description | Stable expression of lncRNA-14327.1, one of the candidate lncRNAs, led to significant upregulation of Kca3.1 protein level, cell migration and invasion abilities, but suppressed cell proliferation and induced cell cycle arrest.Lenti-lncRNA-14327.1 could stabilize the protein of Kca3.1 and subsequently increase intracellular Ca2+ concentration. |
| Pubmed ID | 31819513 |
| Year | 2019 |
| Title | The Long Non-Coding RNA-14327.1 Promotes Migration and Invasion Potential of Endometrial Carcinoma Cells by Stabilizing the Potassium Channel Kca3.1 |
External Links
| Links for RNA-14327.1 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |