Basic Information
| LncRNA/CircRNA Name | RNA-AWPPH |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR , Western blot , in vitro knockdown etc. |
| Sample | OS tissues and paracancerous tissues?,cell lines(OS MG-63 and U2OS, and the osteoblast hFOB1.19 ) |
| Expression Pattern | up-regulated |
| Function Description | AWPPH was highly expressed in OS tissues and cells.AWPPH depletion significantly inhibited OS cell proliferation and migration, and promoted OS cell apoptosis. AWPPH downregulation significantly inhibited the PI3K/AKT pathway. |
| Pubmed ID | 31612016 |
| Year | 2019 |
| Title | Inhibition of Long Non-Coding RNA-AWPPH Decreases Osteosarcoma Cell Proliferation, Migration and Invasion |
External Links
| Links for RNA-AWPPH | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |