Basic Information
| LncRNA/CircRNA Name | LINC-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 |
| Ensemble | ENSG00000258609 |
| Refseq | NR_048536 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc |
| Sample | human breast tissues, including 20 tumor tissue samples and 16 para-carcinoma tissues samples, cell line(MCF-7,293T) |
| Expression Pattern | up-regulated |
| Function Description | Linc-ROR is upregulated in breast tumor tissues.Linc-ROR promotes the proliferation, migration and invasion of breast cancer cells |
| Pubmed ID | 32335998 |
| Year | 2020 |
| Title | Linc-ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR-194-3p targeting MECP2. |
External Links
| Links for LINC-ROR | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |