Basic Information
| LncRNA/CircRNA Name | LINC-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 |
| Ensemble | ENSG00000258609 |
| Refseq | NR_048536 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Luciferase reporter assay etc |
| Sample | colorectal carcinoma tissue,cell lines(HTC116 ) |
| Expression Pattern | up-regulated |
| Function Description | In the present study, Lnc-ROR was highly expressed in colorectal cancers compared with adjacent non-cancerous normal tissues. And the expression level of ROR was also increased in colorectal cancer cells (p < 0.05). |
| Pubmed ID | 32196591 |
| Year | 2020 |
| Title | Long Noncoding RNA ROR Promotes Proliferation and Invasion of Colorectal Cancer by Inhibiting Tumor Suppressor Gene NF2 Through Interacting With miR-223-3p |
External Links
| Links for LINC-ROR | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |