Basic Information
| LncRNA/CircRNA Name | ROR1-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:64094442-64171297 |
| Ensemble | ENSG00000223949 |
| Refseq | NR_110665 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot etc |
| Sample | CC tissues, cell lines (SW756, ME-180, HeLa, C33A, SiHa cells) |
| Expression Pattern | up-regulated |
| Function Description | We found that that the expressions of ROR1-AS1 were distinctly increased in CC tissues and cell lines. Clinical study revealed that high ROR1-AS1 expression was associated with distant metastasis, FIGO stage, and shorter five-year survival. |
| Pubmed ID | 32271410 |
| Year | 2020 |
| Title | Long Noncoding RNA ROR1-AS1 Overexpression Predicts Poor Prognosis and Promotes Metastasis by Activating Wnt/?-catenin/EMT Signaling Cascade in Cervical Cancer |
External Links
| Links for ROR1-AS1 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |