Basic Information
| LncRNA/CircRNA Name | RP11-363E7.4 |
| Synonyms | NA |
| Region | GRCh38_9:19453209-19455173 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR, Western blot |
| Sample | GC tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | overexpression of lncRNA RP11-363E7.4 prevented proliferation, migration, and invasion and induced apoptosis of GC cells. Western blot assay revealed that lncRNA RP11-363E7.4 functioned via the p53, Bax/Bcl-2, ?-catenin pathway. |
| Pubmed ID | 32141108 |
| Year | 2020 |
| Title | Overexpression of long non-coding RNA RP11-363E7.4 inhibits proliferation and invasion in gastric cancer |
External Links
| Links for RP11-363E7.4 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |